Evaluation of novel Saquinavir analogs for resistance mutation compatibility and potential as an HIV-Protease inhibitor drug.
IIS--Integrated Interactome System: a web-based platform for the annotation, analysis and visualization of protein-metabolite-gene-drug interactions by integrating a variety of data sources and tools.
Targeting molecular networks for drug research.
Elucidating pharmacological mechanisms of natural medicines by biclustering analysis of the gene expression profile: a case study on curcumin and Si-Wu-Tang.
Insights from systems pharmacology into cardiovascular drug discovery and therapy.
Human structural proteome-wide characterization of Cyclosporine A targets.
Influenza virus-host interactome screen as a platform for antiviral drug development.
A chemo-centric view of human health and disease.
Identification of novel peroxisome proliferator-activated receptor-gamma (PPARgamma) agonists using molecular modeling method.
Phenotype-based cell-specific metabolic modeling reveals metabolic liabilities of cancer.