Biomedical Informatics Approaches to Identifying Drug-Drug Interactions: Application to Insulin Secretagogues.
Prediction models for drug-induced hepatotoxicity by using weighted molecular fingerprints.
In silico re-identification of properties of drug target proteins.
Pharmacophore-based screening and drug repurposing exemplified on glycogen synthase kinase-3 inhibitors.
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.
Identification of novel MRP3 inhibitors based on computational models and validation using an in vitro membrane vesicle assay.
Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants.
Network mirroring for drug repositioning.
Identification of MYST3 as a novel epigenetic activator of ERalpha frequently amplified in breast cancer.
CarcinoPred-EL: Novel models for predicting the carcinogenicity of chemicals using molecular fingerprints and ensemble learning methods.