Drug interaction


  • DDI
  • Drug drug interaction
  • drug-drug interaction
  • interaction
  • interaction, drug

In DrugBank, this term refers to a change in a drug's effect on the body when the drug is taken with other drugs. A drug interaction can delay, reduce, or enhance the actions of a drug or cause other changes when the drugs are taken together. This can increase or decrease the action of one or all drugs or lead to adverse effects. 1

The DrugBank database includes drug interactions with negative effects resulting from drug interactions and usually does not include drug interactions with beneficial effects.

DrugBank considers product labels and evidence in literature when determining which drug interactions to include in the database. When possible, specific management information for a drug interaction can be obtained from drug interactions and other interactions in the database.


  1. Aids info NIH drug glossary: drug-drug interaction [Link]